Month: July 2014

GHRP-6 Review

GHRP–6 5mgOver the past year we have released several research articles on GHRP-6. You can find them below for your review.

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Click here to download/view the PDF version of this review

GHRP–6

The peptide GHRP 6 is a hexipeptide, meaning that its structure is that of a chain consisting of six amino acids. It is considered to be a secretogogue, meaning that it is a substance that causes a separate substance to be secreted. It has a molecular formula of C46H56N12O6, and its molecular weight is 873.014.

GHRP-6 Basics

In essence, GHRP-6’s overall operational mechanics can be traced to four vital components to an organism, according to scientific study that has been based on animal test subjects. These components are:

  • The pituitary gland – This pea-sized gland located at the bottom of the hypothalamus at the base of the brain is chiefly responsible for the regulation and control of a host of endocrine system-related bodily functions, from growth and metabolism to pain relief and temperature control.
  • The central nervous system – The segment of an animal test subject’s nervous system that consists of the brain and spinal cord. It is responsible for the integration and coordination of all information experienced by an animal test subject
  • The stomach – The digestive system organ that is responsible for the breaking down of food in animal test subjects.
  • The liver – The vital organ that is responsible for detoxification, protein synthesis, and the production of biochemicals vital for digestion.

You can read the full article here: https://blog.extremepeptides.com/ghrp-6/

Looking at buying American Ghrp 6?

You are not the only one! Extreme Peptides has a strong reputation in the peptide industry for the consistency of our purity levels.

Purity is a big factor when buying American Ghrp 6, but how do you know that we aren’t just like the other guys claiming to sell USA made peptides? What is purity? How is purity measured?

You can read the full article here: https://blog.extremepeptides.com/looking-at-buying-american-ghrp-6/

Buy Hexarelin: A (GH secretagogue) that is similar to Ghrp-6

Hexarelin refers to the peptide GH secretagogue which is quite similar in structure to GHRP-6. Because hexarelin is synthetic, its effects are not as potent as the naturalized chemicals.

Using hexarelin to stimulate some hormones will cause an insulin-like growth factor or IGF-1 which is the natural substance used to encourage muscle growth in animals. Unlike similar chemicals, hexarelin does not have any impact on appetite or increase of ghrelin levels.

Effects on Subjects of Varying Ages

Hexarelin has been established as an effective chemical in inducing hormone secretions in small mammals, but the effects and stability of this chemical compared to other common options are largely unknown.

  • To better understand the effects of hexarelin and how they compared to those of common GH stimulators such as GHRP6, GHRP1 or GHRP2, secretions were studied in rats of varying ages and results were compared to the known stable chemical 2-methyl-trp.
  • In 10 day old rats Trp was substituted with 2-methyl-trp and a hexapeptide hexarelin to achieve GH secretion. The chemicals were successful in achieving this stimulation.

In trials, hexarelin appeared to be more effective than GHRP6 in eliciting the desired response. This indicates that hexarelin could be used as an effective releasing agent that could act as a tool for both diagnostic and therapeutic work in clinical practice in the future.

You can read the full article here https://blog.extremepeptides.com/buy-hexarelin/

The Impact of GHRP6 on obese Conditions

Obesity can interfere with the function of organs such as the pituitary gland or pancreas. If these organs cannot receive the proper messages then the system will fail to produce proper levels of chemicals, such as insulin.

Studies are undergoing to determine the effectiveness of using artificial hormones to help regulate these hormone levels. The growth chemical GHRP6 is currently being studied for such a purpose, though it will take some time before any coherent results are determined.

You can read the full article here https://blog.extremepeptides.com/the-impact-of-ghrp6-on-obese-conditions-2/

What Is GHRP-6?

GHRP-6 is a peptide which comprises the AA sequence of H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. In studies GHRP-6 has shown biological actions similar to the naturally occurring hunger stimulating peptide ghrelin.

GHRP-6 contains D-amino acids that are entirely synthetic, lacks opioid activity, and shares no sequence relation with GHRH.

It has also been shown that GHRP-6 can lead to re-stimulation of the natural production of GH.

Studies have shown that GHRP-6 increases the secretion of IGF-1 by the liver of some lab rats (Insulin-Like Growth Factor 1), which is speculated to be a required component in the anabolic mechanisms leading to the action of GH. It also appears that GHRP-6 has positive implications for the central nervous system, as ghrelin is known to protect neurons.

You can read the full article here https://blog.extremepeptides.com/what-is-ghrp-6-2/

Qualities of GHRP6 – Additional GHRP Releasers

There are a variety of GHRP chemicals, both in natural and artificial settings.

These hormones are designed to time the growth and creation of additional tissue. In scientific study these hormones are used to determine their effects of various chemicals.

Additional GHRP Releasers

The GHRP series is a group of hexapeptides that is designed to mimic natural growth releasers.

  • Basic versions of these peptides include GHRP1, GHRP2 and GHRP6. These are available in natural forms, though the artificial versions of these chemicals have slightly different properties and are not considered for bodily use.
  • GHRP6 has been used as a template to help create additional peptides that have tetra penta and pseudotripepide properties.
  • These have a very different structural homology and have different receptors that do not respond to the pituitary and hypothalamic glands the way the natural substances would.

You can read the full article here https://blog.extremepeptides.com/qualities-of-ghrp6/

Buy GHRP-6 From Dedicated Research Suppliers

GHRP-6 includes an unnatural D-amino acid chain. It is a hexapeptide that has a 6 amino acid chain. This peptide was developed to use in experiments that required, specifically GH secretagogues. This particular peptide is capable of stimulating GH in a natural setting, which many artificial peptides are not capable of producing. The unique amino acid structure of this peptidecan blocks somatostatin.

There are several suppliers that offer GHRP-6 in quantities that have been carefully measured for use in laboratory settings. Research quality GHRP-6 should be carefully inspected to ensure that it is not impure or contains any fillers, such as mannitol that could throw off the results of your study. Fast processing is also essential to ensure that your peptides arrive in a reasonable amount of time to begin your experiment.

Dedicated Research GHRP-6 Suppliers

Ordering GHRP-6 from a dedicated research service ensures a product that is high in quality, guaranteeing that it will be suitable for a wide range of laboratory applications.

  • Seek out a supplier that offers 99 percent pure GHRP-6 that has no binding agents or fillers that could affect the quality of your experiment.
  • All products should be clean and professionally packaged to prevent potential contamination of the product during transit.
  • Large quantities of GHRP-6 should come in a resalable container that can be stored in cold temperatures to ensure stability of the product.

You can read the full article here https://blog.extremepeptides.com/buy-ghrp-6/

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Phospho DSIP – Part 1

Download or view the PDF version of this article by clicking here

Phospho DSIP is a peptide that is considered to be a neuropeptide.  What this means is, it is a peptide that is used by neurons in order to communicate with each other.  It is occasionally known by the alternative names DSIP or Delta Sleep Inducing Peptide.  It has a molecular formula of C35H49N10O18P1, and it has a molecular weight of 928.8.  When it is administered to animal test subjects for purposes of scientific study, its appearance is that of a white powder.

Phospho DSIP at a Glance

According to scientific study based on animal test subjects, Phospho DSIP is considered to be an amphiphilic peptide, meaning that it contains both hydrophilic (that is, water-loving) and lipophilic (that is, fat-loving) properties.  It has been found within the body as a free form, and it has been found in bound form in the following structures:

  • The hypothalamus – This is the segment of the brain that links the endocrine system to the nervous system through the pituitary gland.
  • The pituitary gland – This is the pea-sized gland that is located at the bottom of the hypothalamus at the base of the brain and is responsible for the regulation and control of a host of endocrine system-related functions such as growth, metabolism, temperature regulation, and more.
  • The limbic system – This represents the complex set of brain structures that collectively support a variety of emotional-based aspects, such as behavior, motivation, and long-term memory.
  • Various peripheral organs, tissues, and body fluids located throughout the body.

In addition, Phospho DSIP has been shown to co-localise with various peptide and non-peptide mediators.  The mediators themselves differ depending on where Phospho DSIP is located.

While it has been determined that Phospho DSIP can be found in several different places within an animal test subject’s body, scientific study has yet to precisely pinpoint where the peptide originates.

Functionality of Phospho DSIP

Scientific study that has been based on animal test subjects has determined that the presence of Phospho DSIP can help to boost the regulation and control of several different processes throughout the body.  Because of the abundance of locations in which Phospho DSIP resides within an animal test subject’s body, scientific study has determined that the peptide itself is rather versatile.  It has been thought to play a part in a host of different roles throughout the body.

For instance, the peptide has been determined to play a role in the process of endocrine regulation.  It has been shown to decrease basal corticotropin level and inhibit its release.  It also stimulates the release of luteinizing hormone, somatoliberin and somatorophin secretion as it inhibits somatostatin secretion.

Phospho DSIP also plays a part in various types of physiological processes.  Some of these processes include limiting stress, normalizing blood pressure and myocardial contraction, and enhancing the efficiency of oxidative phospoylation.  This latter attribute has led to the suggestion that it may possess various antioxidant effects.

Because Phospho DSIP is connected to the regulation and control of so many diverse bodily processes, scientific study that has been based on animal test subjects has been able to derive a host of different theoretical benefits that have been built around the peptide’s presence.  These benefits that have been hypothesized touch upon both the mental and the physical, thus further demonstrating that the peptide does have a connection with various parts of the brain.

Phospho DSIP and Cancer

Scientific study that has been based on animal test subjects has determined that Phospho DSIP could conceivably contain certain properties that can be considered anticarcinogenic in nature.  What this means is, it has been shown to be a substance that counteracts the effects of cancer causing agents or inhibits the development of cancer.  This theory was developed in lieu of a study that was conducted on lab mice, in which a preparation of the peptide was injected subcutaneously over the mice’s lifetime.  It was shown that the presence of spontaneous tumor incidence decreased significantly.  This study in turn led to the theory that the presence of the peptide could be a key combatant in the treatment of cancer.  It has also led to the notion that it could be used as a means to prevent cancerous tumors from developing in the first place.

Phospho DSIP and Anti-Aging

Scientific study on animal test subjects has also determined that the presence of Phospho DSIP could possess geroprotective, or anti-aging, effects.  Studies have indicated that the presence of the peptide has the capacity to slow down the age-related switching-off of oestrous function in female animal test subjects, and it also was shown to decrease the frequency of various chromosome aberrations in bone marrow cells, some of which may ultimately serve to shorten a lifespan.

Click here to read Phospho DSIP – Part 2