Anastrozole – Chemical Mechanisms And Study

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Anastrozole is commonly produced under the name Arimidex. This chemical is not naturally occurring and is currently not available outside of laboratory settings. Scientists are currently investigating this chemical’s impact on estrogen receptors or conversion mechanisms– both in an artificial and natural state.

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Anastrozole was designed to act as an aromatase-inhibiting chemical that may have applications toward metastasis. Potential use in combatting the effects of hyperplasia is currently being studied, as is the reactions of anastrozole when interacting with the synthesis of estrogen.

The patent on this chemical expired in 2010 which has opened the door for additional testing and research on these effects.

Chemical Mechanisms

Anastrozole is prepared in laboratory environments by subjecting mesitylene to a radical brominisation process.

  • Anastrozole is prepared by substituting two benzylic for cyanide, treating the chemical with potassium cyanide using a phase transfer condition.
  • The methylation of this chemical with sodium hydridie and methyl iodide creates an acidic compound that includes several methyl groups and hydrogen atoms.
  • Treating bromine along with benzyl peroxide will create a corresponding benzyl bromide reaction that creates the base for the aromatase inhibitor.

Additional compounds can be created using a similar process. This allows manufacturers to create variations on the compound to increase or decrease the strength of the chemical as necessary. Varying compositions of anastrozole can be used in laboratory settings to act as carriers or diluents based on the nature of the study.

Study

Studies are ongoing to determine the usefulness of using anastrozole for medical application in the future.

Ongoing studies are in progress to assist in determining the inhibiting properties of anastrozole as well as the process of compounding these chemicals to create a variation of strengths of this chemical.

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Bremelanotide PT-141 Study – Potential Use

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Bremelanotide

Bremelanotide is a compound that is currently under investigation for its potential uses in managing reperfusion injury, female sexual dysfunction or hemorrhagic shock. The chemical may also see success in managing modulate inflammation or limiting the effects of ischemia.

Study – Potential Use Erectile Dysfunction

One study has explored the potential use of bremelanotide as a replacement for natural peptide melanocyte stimulating hormones for the sake of treating erectile dysfunction.

  • The goal of this study was to determine if the effects of bremelanotide stimulating sexual desire that was shown in male rats could be replicated in the brains of female rats. To do this, hormone primed female rats in a control group and a test group that were treated with bremelanotide and known to have consummatory sexual disorders was introduced to a group of male rats and the reactions were measured.
  • Heart racing, hops and darts, pacing and customary sexual behaviors were assessed while the brain was stimulated. The stimulation of specific molecular markers within the brain was examined to determine arousal in the female subjects.
  • Results indicated that the females saw an increase in sexual behavior when bremelanotide was applied to the limbic and hypothalamic regions of their brains. It is suggested that this was because the chemical that stimulated the mPOA terminals, leading to activated dopamine in the brain.

Additional study is necessary to determine the extent of the effects bremelanotide has on the brain and natural stimulating chemicals. Research companies buy bremelanodtide in our online store located right here at www.extremepeptides.com.

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Where to Buy IGF-1 LR3 And Specific Chemical Makeup

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Discount NewsletterIgf-1 lr3 is the chemical name for insulin like growth factor 1 long r3. In research studies it was also found that this chemical is responsible for hyperplasia that causes the muscles cells to split and form new tissue. Experiments with lab rats revealed that increasing this natural peptide will increase muscles cell density.

The artificial version of igf-1 lr3 is designed to promote protein synthesis and nitrogen retention in a similar fashion to the natural chemical found in animal cells. This will help to make the muscles grow, not by adding additional bulk to the tissue, but by encouraging new tissue to grow to create a larger amount of muscle cells.

Applying this chemical to an animal’s body has also been found to increase the body’s ability to burn fat. Some suspect that this also increases neuro function in animals, but studies are currently inconclusive.

Specific Chemical Makeup

Igf-1 lr3 is made up of 70 amino acids which help it to be identified as growth factors that will impact the skeletal muscle and peripheral tissues like those released naturally from the animal’s liver.

  • Chemical versions of igf-1 lr3 are not sterile and therefore not considered appropriate for injections. It is also not considered appropriate for ingestion.
  • This chemical acts as a neruoprmotor and neruoprotector that may have an impact on the memory, reflexes and learning ability of the animal subjects regularly exposed to this peptide during research.
  • The chemical is designed to increase the production of connective tissue while ensuring the proper bone density in the animal’s body. However, ongoing research is being used to determine if an animal reacts to the synthesized version of this chemical the way it does the natural peptide produced by the liver.
  • This chemical should not be confused with lr3IGF-1. This is an 83 amino acid that is designed to mimic the effects of the human igf-1 rather than that that is present in smaller animals. Lr3IGF-1 will substitute Arg for the Glu in its position, and help to manage the extension of the peptide in the N-terminus in the body.

Research is ongoing to determine the specific reactions to natural igf-1 and its impact on the anabolic activities in an animal’s body. Research is also hoping to indicate how an animal’s body relates to the synthesized versions of this chemical as opposed to that which is naturally produced by the liver.

Igf-1 can be administered to animal subjects on its own because the structure and size mimics that of insulin, making it easy for the animal’s body to address the peptide as though it were a natural chemical. However, studies have found that igf-1 lr3 is considerably more effective in building new muscle tissue and burning fat. Ongoing studies comparing the two are largely focusing on providing more information on how these peptides affect diseases and potential side effects.

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